Stop ibuprofen (and all NSAIDs) at least 5 days before colonoscopy.
Why
- NSAIDs inhibit platelet COX-1 → impaired clotting → increased bleeding risk during polypectomy/biopsy.
- Colonoscopy often involves polyp removal; bleeding is a known complication.
- 5 days allows platelet turnover (lifespan 7–10 days) to restore normal function.
Other Meds to Hold
- Aspirin (7–10 days if for primary prevention; consult cardiologist if secondary)
- Other NSAIDs (naproxen, celecoxib, meloxicam)
- Anticoagulants/antiplatelets (per prescribing doctor's protocol)
- Supplements: fish oil, vitamin E, ginkgo, garlic (1 week)
Safe to Continue
- Acetaminophen (Tylenol) for pain/fever
- Most prescription meds (BP, thyroid, etc.)—confirm with doctor
Follow your gastroenterologist's specific instructions exactly.
