The brain uses more energy—about 20% of resting metabolic rate despite being only 2% of body weight. The heart, while continuously pumping, consumes less total energy (~7–10% of resting expenditure).
The brain's high demand fuels: synaptic signaling, ion gradient maintenance, neurotransmitter cycling, and constant information processing. Even at rest, the “default mode network” is active. Energy shortage rapidly impairs consciousness and cognition.

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